Topiramate is one of the latest generation antiepileptic agents. This medicine is particularly used to manage generalised tonic-clonicseizures. These involve sudden stiffening with muscle contractions and spasms.
Topiramate acts both on the receptors for GABA (gamma-aminobutyric acid), a neurotransmitter, the activity of which it increases. It also acts on the sodium channels involved in propagation of the nerve impulse.
Topiramate can cause mood disorders and confusion. It has also been associated with weight loss or even anorexiain some patients.
Topiramate is a latest generation medicine for epilepsy. © Phovoir