Some non-antibiotic antibacterial agents can be applied as a gel or cream topically. These act on the bacterial proliferation in the skin and therefore on the development ofacne. Benzoyl peroxide is one of these topical antibacterial antiacne agents.
These medicines work against acne by reducing colonisation of the skin by Propionibacterium acnes. Benzoyl peroxide also reduces free fatty acids which have an irritating comedogenic effect. On the other hand this topical medicine has no proven action on sebaceous secretions.
Benzoyl peroxide can cause dry skin. It can also discolour clothing and hair. In addition, some patients can suffer allergic reactions, although fortunately these are rare. The gel applications appear to be better tolerated.
The main topical antibacterial antiacne preparation is called benzoyl peroxide. © Phovoir